The GUI (nod32.exe) in NOD32 2.5 runs with SYSTEM privileges when the scheduler runs a scheduled on-demand scan, which allows local users to execute arbitrary code during a scheduled scan via unspecified attack vectors.
Buffer overflow in Eset Software NOD32 for UNIX before 1.013 allows local users to execute arbitrary code via a long path name.
The SysInspector AntiStealth driver (esiasdrv.sys) 3.0.65535.0 in ESET System Analyzer Tool 1.1.1.0 allows local users to execute arbitrary code via a certain METHOD_NEITHER IOCTL request to \Device\esiasdrv that overwrites a pointer.