The sample web application in web2py before 2.14.2 might allow remote attackers to execute arbitrary code via vectors involving use of a hardcoded encryption key when calling the session.connect function.
Web2py versions 2.14.5 and below was affected by Local File Inclusion vulnerability, which allows a malicious intended user to read/access web server sensitive files.
The secure_load function in gluon/utils.py in web2py before 2.14.2 uses pickle.loads to deserialize session information stored in cookies, which might allow remote attackers to execute arbitrary code by leveraging knowledge of encryption_key.