Deploy strong code integrity policies to allow only authorized apps to run.
Use endpoint detection and response solutions that can automaticalkly detect and remediate suspicious activities.
Maintain a highly secure build and update infrastructure by immediately applying security patches for OS and software, implementing mandatory integrity controls to ensure only trusted tools run, and requiring multi-factor authentication for admins.
Require SSL for update channels and implement certificate transparency based verification.
Sign update packages and BIOS patches.
Use hardware security modules/trusted platform modules to verify authenticity using hardware-based cryptography.